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Symbol Name ID |
Fgf8
fibroblast growth factor 8 MGI:99604 |
| Darker colors indicate more annotations |
| Human Phenotypes | Cleft lip |
High palate |
Anosmia |
Hyposmia |
| Disease(s) Associated with FGF8 | ||||
| hypogonadotropic hypogonadism 6 with or without anosmia |
| Mouse Phenotypes | abnormal pharyngeal arch artery morphology |
abnormal fourth pharyngeal arch artery morphology |
absent fourth pharyngeal arch artery |
fourth pharyngeal arch artery hypoplasia |
abnormal sixth pharyngeal arch artery morphology |
absent sixth pharyngeal arch artery |
abnormal third pharyngeal arch artery morphology |
enlarged third pharyngeal arch artery |
third pharyngeal arch artery hypoplasia |
abnormal craniofacial morphology |
absent Meckel's cartilage |
absent molars |
abnormal mandible morphology |
abnormal maxilla morphology |
absent incus |
abnormal craniofacial development |
abnormal pharyngeal arch morphology |
small first pharyngeal arch |
abnormal pharyngeal arch mesenchyme morphology |
small pharyngeal arch |
pharyngeal arch hypoplasia |
decreased tongue size |
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| Availability | Mouse Genotype | ||||||||||||||||||||||
| Fgf8tm1.1Jyhl/Fgf8tm1.1Jyhl | |||||||||||||||||||||||
| Fgf8tm1.1Mrt/Fgf8tm1.2Mrt | |||||||||||||||||||||||
| Fgf8tm1Mrc/Fgf8tm3Mrc | |||||||||||||||||||||||
| Fgf8tm1Moon/Fgf8tm1Moon Mesp1tm2(cre)Ysa/Mesp1+ (conditional) |
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| Fgf8tm1.2Mrt/Fgf8tm1.3Mrt Tg(Nes-cre)1Atp/0 (conditional) |
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| Fgf8tm1.3Mrt/Fgf8tm1.4Mrt Nkx2-5tm1(cre)Rjs/Nkx2-5+ (conditional) |
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| Fgf8tm1.3Mrt/Fgf8tm2Mrt Nkx2-5tm1(cre)Rjs/Nkx2-5+ (conditional) |
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| Fgf8tm1Mrc/Fgf8tm1Moon Tfap2atm1(cre)Moon/Tfap2a+ (conditional) |
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| Fgf8tm1Mrc/Fgf8tm1Moon Hoxa3tm1(cre)Moon/Hoxa3+ (conditional) |
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| Fgf8tm1Mrc/Fgf8tm2Mrc Tfap2atm1(cre)Moon/Tfap2a+ (conditional) |
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| Fgf8tm1Mrc/Fgf8tm2Mrc Hoxa3tm1(cre)Moon/Hoxa3+ (conditional) |
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| Fgf8tm2Moon/Fgf8tm1Mrc Isl1tm1(cre)Sev/Isl1+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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