Symbol
Name
ID

Aldh2
aldehyde dehydrogenase 2, mitochondrial
MGI:99600

Phenotype annotations related to behavior/neurological

Darker colors indicate more annotations

Human Phenotypes	Abdominal pain	Anorexia	Poor appetite	Back pain	Polydipsia	Polyphagia	Addictive alcohol use	Chronic fatigue
Disease(s) Associated with ALDH2	Abdominal pain	Anorexia	Poor appetite	Back pain	Polydipsia	Polyphagia	Addictive alcohol use	Chronic fatigue
alcohol dependence
pancreatic cancer
type 1 diabetes mellitus

Mouse Phenotypes

decreased alcohol consumption

enhanced behavioral response to alcohol

abnormal object recognition memory

impaired spatial learning

abnormal spatial working memory

abnormal response to novel object

abnormal response to tactile stimuli

abnormal startle reflex

abnormal nociception after inflammation

hyperalgesia

impaired exercise endurance

Availability

Mouse Genotype

Aldh2^{Gt(OST7285)Lex}/Aldh2^{Gt(OST7285)Lex}

Aldh2^tm1.1Mak/Aldh2^tm1.1Mak

Aldh2^{tm1a(EUCOMM)Wtsi}/Aldh2^{tm1a(EUCOMM)Wtsi}

Aldh2^tm1Bcgen/Aldh2^tm1Bcgen

Tg(EIF1AX-Aldh2*E487K)101Oht/Tg(EIF1AX-Aldh2*E487K)101Oht

Aldh2^tm1.1Mak/Aldh2⁺

Aldh2^tm1Dmro/Aldh2⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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