Symbol Name ID |
Chuk
conserved helix-loop-helix ubiquitous kinase MGI:99484 |
* | Aspects of the system are reported to show a normal phenotype. |
! | Indicates phenotype varies with strain background. |
Darker colors indicate more annotations |
Human Phenotypes | Thin skin |
Disease(s) Associated with CHUK | |
fetal encasement syndrome |
Mouse Phenotypes | integument phenotype |
abnormal keratinocyte differentiation |
increased keratinocyte proliferation |
abnormal mammary gland growth during pregnancy |
abnormal mammary gland epithelium morphology |
abnormal mammary gland alveolus morphology |
abnormal lactation |
impaired skin barrier function |
skin inflammation |
sparse hair |
abnormal hair follicle morphology |
abnormal hair follicle development |
abnormal vibrissa follicle morphology |
absent vibrissae |
abnormal skin morphology |
abnormal epidermal layer morphology |
abnormal epidermis stratum basale morphology |
abnormal epidermis stratum corneum morphology |
absent epidermis stratum corneum |
parakeratosis |
abnormal epidermis stratum granulosum morphology |
absent epidermis stratum granulosum |
abnormal epidermis stratum spinosum morphology |
abnormal epidermis suprabasal layer morphology |
epidermal desquamation |
epidermal hyperplasia |
thick epidermis |
abnormal skin appearance |
shiny skin |
skin lesions |
tight skin |
translucent skin |
wrinkled skin |
abnormal skin condition |
thick skin |
increased skin tumor incidence |
increased skin papilloma incidence |
increased skin squamous cell carcinoma incidence |
abnormal skin physiology |
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Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||
Chuktm1.1Mpa/Chuktm1.1Mpa | ||||||||||||||||||||||||||||||||||||||||
Chuktm1Aki/Chuktm1Aki | ||||||||||||||||||||||||||||||||||||||||
Chuktm1Mka/Chuktm1Mka | ||||||||||||||||||||||||||||||||||||||||
Chuktm1Ver/Chuktm1Ver | ||||||||||||||||||||||||||||||||||||||||
Chuktm2Mka/Chuktm2Mka | ||||||||||||||||||||||||||||||||||||||||
Chuktm2Yhu/Chuktm2Yhu | * | |||||||||||||||||||||||||||||||||||||||
Chuktm1Mpa/Chuktm1Mpa Tg(KRT14-cre)1Cgn/? (conditional) |
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Chuktm1Yhu/Chuktm1Yhu Tg(KRT5-cre)5132Jlj/0 (conditional) |
! | |||||||||||||||||||||||||||||||||||||||
Chuktm1Yhu/Chuktm1Yhu Tg(KRT14-cre)1Cgn/0 (conditional) |
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Chuktm1Yhu/Chuktm1Yhu Tg(MMTV-cre)4Mam/0 (conditional) |
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Chuktm1Yhu/Chuktm1Yhu Tg(Krt1-15-cre/PGR*)22Cot/0 (conditional) |
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Chuktm1Yhu/Chuktm1Yhu Tg(Krt1-5-cre/ERT)1Ipc/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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