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Symbol
Name
ID

Notch3
notch 3
MGI:99460

Phenotype annotations related to behavior/neurological

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Pseudobulbar paralysis	Urinary incontinence	Atypical behavior	Abulia	Personality changes	Hypernasal speech
Disease(s) Associated with NOTCH3	Pseudobulbar paralysis	Urinary incontinence	Atypical behavior	Abulia	Personality changes	Hypernasal speech
CADASIL 1
lateral meningocele syndrome

Mouse Phenotypes		behavior/neurological phenotype	lethargy	decreased exploration in new environment	abnormal motor capabilities/coordination/movement	ataxia	hunched posture	paresis
Availability	Mouse Genotype	behavior/neurological phenotype	lethargy	decreased exploration in new environment	abnormal motor capabilities/coordination/movement	ataxia	hunched posture	paresis
	Notch3^tm1.1Dwr/Notch3^tm1.1Dwr
	Notch3^em1Ecan/Notch3⁺	*
	Notch3^tm1.1Dwr/Notch3⁺
	Tg(Lck-Notch3)#Issc/0

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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