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Symbol Name ID |
Xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1 MGI:99137 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | cellular phenotype |
oligozoospermia |
abnormal spermatocyte morphology |
abnormal spermatogonia morphology |
abnormal mitochondrial morphology |
increased embryonic tissue cell apoptosis |
increased neuron apoptosis |
increased testis apoptosis |
abnormal neuron differentiation |
asthenozoospermia |
abnormal mitochondrial ATP synthesis coupled electron transport |
abnormal DNA repair |
abnormal mitochondrial physiology |
oxidative stress |
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| Availability | Mouse Genotype | ||||||||||||||
| Meox2tm1(cre)Sor/Meox2+ Xrcc1tm1Pmc/Xrcc1tm1Pmc (conditional) |
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| Xrcc1tm1Pmc/Xrcc1tm1Pmc Tg(Nes-cre)1Kln/0 (conditional) |
* | ||||||||||||||
| Alpltm1(cre)Nagy/Alpl+ Xrcc1tm1Pmc/Xrcc1tm1Pmc (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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