|
Symbol Name ID |
Trp53
transformation related protein 53 MGI:98834 |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating IgA level |
Increased circulating IgG level |
Decreased circulating antibody level |
Paraproteinemia |
Hypercalcemia |
Increased LDL cholesterol concentration |
Hypercholesterolemia |
Hypertriglyceridemia |
Elevated circulating creatinine concentration |
Hyperproteinemia |
Elevated circulating hepatic transaminase concentration |
Abnormal circulating lactate dehydrogenase concentration |
Increased circulating lactate dehydrogenase concentration |
Elevated circulating alkaline phosphatase concentration |
Glucose intolerance |
Diabetes mellitus |
Type II diabetes mellitus |
Impaired glucose tolerance |
Joint swelling |
Pleural effusion |
Fever |
Abnormality of vitamin B12 metabolism |
Increased level of L-fucose in urine |
Amyloidosis |
Increased circulating free T3 |
Increased circulating free T4 concentration |
Decreased thyroid-stimulating hormone level |
| Disease(s) Associated with TP53 | |||||||||||||||||||||||||||
| coronary artery disease | |||||||||||||||||||||||||||
| Graves' disease | |||||||||||||||||||||||||||
| multiple myeloma | |||||||||||||||||||||||||||
| osteosarcoma | |||||||||||||||||||||||||||
| pancreatic cancer | |||||||||||||||||||||||||||
| stomach cancer |
| Mouse Phenotypes | abnormal response to cardiac infarction |
increased DNA replication |
decreased circulating insulin-like growth factor I level |
increased circulating interferon-gamma level |
increased circulating interleukin-3 level |
increased circulating interleukin-5 level |
increased circulating interleukin-6 level |
increased circulating tumor necrosis factor level |
decreased circulating creatine kinase level |
abnormal iron homeostasis |
abnormal iron level |
abnormal protein level |
decreased mortality induced by ionizing radiation |
increased mortality induced by ionizing radiation |
increased mortality induced by gamma-irradiation |
abnormal physiological response to xenobiotic |
increased susceptibility to xenobiotic induced morbidity/mortality |
decreased incidence of tumors by chemical induction |
increased incidence of tumors by chemical induction |
delayed wound healing |
enhanced wound healing |
|
| Availability | Mouse Genotype | |||||||||||||||||||||
| Trp53tm1.1Hwan/Trp53tm1.1Hwan | ||||||||||||||||||||||
| Trp53tm1.2Awbr/Trp53tm1.2Awbr | ||||||||||||||||||||||
| Trp53tm1Brd/Trp53tm1Brd | ||||||||||||||||||||||
| Trp53tm1Tyj/Trp53tm1Tyj | ||||||||||||||||||||||
| Trp53tm2Wahl/Trp53tm2Wahl | ||||||||||||||||||||||
| Trp53tm3.1Glo/Trp53tm3.1Glo | ||||||||||||||||||||||
| Trp53tm1.1Hwan/Trp53+ | ||||||||||||||||||||||
| Trp53tm1b(EUCOMM)Hmgu/Trp53+ | ||||||||||||||||||||||
| Trp53tm1Brd/Trp53+ | ||||||||||||||||||||||
| Trp53tm1Ldo/Trp53+ | ||||||||||||||||||||||
| Trp53tm1Tyj/Trp53+ | ||||||||||||||||||||||
| Tg(Trp53)1Srn/0 | ||||||||||||||||||||||
| Tg(Trp53A135V)L3Ber/0 | ||||||||||||||||||||||
| Tg(Trp53R172H)8512Jmr/0 | ||||||||||||||||||||||
| Tg(Trp53R172L)4491Jmr/0 | ||||||||||||||||||||||
| Trp53tm1Brn/Trp53tm1Brn (conditional) | ||||||||||||||||||||||
| Trp53tm1Brn/Trp53tm1Brn Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+ (conditional) |
||||||||||||||||||||||
| Trp53tm1Brn/Trp53+ Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+ (conditional) |
||||||||||||||||||||||
| Trp53tm3Tyj/Trp53+ Tg(Wap-cre)11738Mam/0 (conditional) |
||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/16/2024 MGI 6.23 |
|
|
|
||
Analysis Tools