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Symbol
Name
ID
Top2b
topoisomerase (DNA) II beta
MGI:98791
Phenotype annotations related to vision/eye
Darker colors indicate more annotations

Mouse Phenotypes
abnormal photoreceptor outer segment morphology
abnormal retina cone cell outer segment morphology
abnormal retina rod cell outer segment morphology
photoreceptor outer segment degeneration
abnormal retina cone cell morphology
retina cone cell degeneration
abnormal retina rod cell morphology
retina photoreceptor degeneration
abnormal retina pigment epithelium morphology
abnormal eye morphology
persistence of hyaloid vascular system
thin retina outer nuclear layer
abnormal retina outer plexiform layer morphology
abnormal retina outer limiting membrane morphology
Availability Mouse Genotype
Top2bem1(IMPC)Mbp/Top2b+
Tg(Dkk3-cre)D9Tfur/0
Top2btm2Jcw/Top2btm2Jcw  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory