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Symbol
Name
ID
Thrb
thyroid hormone receptor beta
MGI:98743
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Increased circulating thyroglobulin concentration
Diabetes mellitus
Type II diabetes mellitus
Increased circulating free T3
Increased circulating free T4 concentration
Increased circulating T4 concentration
Elevated circulating thyroid-stimulating hormone concentration
Epiphyseal stippling
Disease(s) Associated with THRB
selective pituitary thyroid hormone resistance
thyroid hormone resistance syndrome

Mouse Phenotypes
homeostasis/metabolism phenotype
abnormal circulating hormone level
decreased circulating insulin-like growth factor I level
decreased circulating thyroid-stimulating hormone level
increased circulating thyroid-stimulating hormone level
decreased circulating thyroxine level
increased circulating thyroxine level
increased circulating triiodothyronine level
increased circulating levels of thyroid hormone
decreased circulating glycerol level
abnormal pituitary hormone level
increased thyroid-stimulating hormone level
abnormal thyroid hormone level
increased thyroxine level
increased triiodothyronine level
abnormal response/metabolism to endogenous compounds
Availability Mouse Genotype
Thrbtm1.1Syc/Thrbtm1.1Syc
Thrbtm1Df/Thrbtm1Df
Thrbtm1Ehs/Thrbtm1Ehs *
Thrbtm1Few/Thrbtm1Few
Thrbtm1Olc/Thrbtm1Olc
Thrbtm2a(EUCOMM)Wtsi/Thrbtm2a(EUCOMM)Wtsi
Thrbtm2Df/Thrbtm2Df
Thrbtm2Few/Thrbtm2Few
Thrbtm3.1Df/Thrbtm3.1Df
Thrbtm3Few/Thrbtm3Few
Thrbtm4Few/Thrbtm4Few
Thrbtm6.1Few/Thrbtm6.1Few *
Thrbtm1.1Syc/Thrb+
Thrbtm2Few/Thrb+
Thrbtm6.1Few/Thrb+ *
Thrbtm1Mkni/Thrbtm1Mkni
Hprt1tm1(TG-cre)1Sasr/Y  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory