|
Symbol Name ID |
Tgfb1
transforming growth factor, beta 1 MGI:98725 |
| * | Aspects of the system are reported to show a normal phenotype. |
| ! | Indicates phenotype varies with strain background. |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating IgA level |
Increased circulating IgG level |
Decreased circulating antibody level |
Paraproteinemia |
Abnormality of metabolism/homeostasis |
Hypercalcemia |
Elevated circulating creatinine concentration |
Hyperproteinemia |
Elevated circulating hepatic transaminase concentration |
Elevated circulating alkaline phosphatase concentration |
Elevated erythrocyte sedimentation rate |
Elevated sweat chloride |
Dehydration |
Joint swelling |
Pleural effusion |
Food intolerance |
Abnormality of vitamin B12 metabolism |
Hypercalciuria |
Decreased level of D-mannose in urine |
Amyloidosis |
| Disease(s) Associated with TGFB1 | ||||||||||||||||||||
| atopic dermatitis | ||||||||||||||||||||
| Behcet's disease | ||||||||||||||||||||
| Camurati-Engelmann disease | ||||||||||||||||||||
| cystic fibrosis | ||||||||||||||||||||
| factor VIII deficiency | ||||||||||||||||||||
| multiple myeloma |
| Mouse Phenotypes | homeostasis/metabolism phenotype |
increased circulating creatinine level |
decreased circulating insulin level |
decreased circulating leptin level |
increased circulating alanine transaminase level |
abnormal atrial thrombosis |
edema |
improved glucose tolerance |
abnormal interferon level |
abnormal interleukin level |
abnormal physiological response to xenobiotic |
increased susceptibility to kidney reperfusion injury |
|
| Availability | Mouse Genotype | ||||||||||||
| Tgfb1tm1(Tgfb3)Kul/Tgfb1tm1(Tgfb3)Kul | |||||||||||||
| Tgfb1tm1Doe/Tgfb1tm1Doe | * | ! | |||||||||||
| Tgfb1tm1N/Tgfb1tm1N | |||||||||||||
| Tgfb1tm1Doe/Tgfb1+ | |||||||||||||
| B9d2/Tgfb1tm1Flv/Tgfb1tm2Flv Tg(Cd4-cre)1Cwi/0 (conditional) |
|||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 05/07/2024 MGI 6.23 |
|
|
|
||
Analysis Tools