Symbol
Name
ID

Tgfb1
transforming growth factor, beta 1
MGI:98725

Phenotype annotations related to growth/size/body

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Splenomegaly	Hepatosplenomegaly	Hepatomegaly	Delayed puberty	Tall stature	Disproportionate tall stature	Slender build	Decreased body mass index	Failure to thrive	Weight loss
Disease(s) Associated with TGFB1	Splenomegaly	Hepatosplenomegaly	Hepatomegaly	Delayed puberty	Tall stature	Disproportionate tall stature	Slender build	Decreased body mass index	Failure to thrive	Weight loss
Camurati-Engelmann disease
cystic fibrosis
eosinophilic esophagitis
multiple myeloma

Mouse Phenotypes

abnormal tooth morphology

abnormal incisor morphology

abnormal incisor color

misaligned incisors

ameloblast degeneration

abnormal tooth mineralization

abnormal enamel morphology

abnormal tooth attrition

malocclusion

embryonic growth retardation

growth/size/body region phenotype

decreased body weight

weight loss

cachexia

decreased body height

Availability

Mouse Genotype

Tgfb1^{tm1(Tgfb3)Kul}/Tgfb1^{tm1(Tgfb3)Kul}

Tgfb1^tm1Doe/Tgfb1^tm1Doe

Tgfb1^tm1N/Tgfb1^tm1N

Tgfb1^tm1Rif/Tgfb1^tm1Rif

Tg(Lck-cre)548Jxm/?
Tgfb1^tm2.1Doe/Tgfb1^tm2.1Doe (conditional)

B9d2/Tgfb1^tm1Flv/Tgfb1^tm2Flv
Tg(Cd4-cre)1Cwi/0 (conditional)

B9d2/Tgfb1^tm1Flv/Tgfb1^tm2Flv
Tnfrsf4^tm2(cre)Nik/Tnfrsf4⁺ (conditional)

B9d2/Tgfb1^tm1Flv/Tgfb1^tm2Flv
Foxp3^{tm4(YFP/icre)Ayr}/Foxp3⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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