|
Symbol Name ID |
Sox2
SRY (sex determining region Y)-box 2 MGI:98364 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Sclerocornea |
Cataract |
Iris coloboma |
Optic nerve aplasia |
Optic nerve hypoplasia |
Anophthalmia |
Microphthalmia |
Coloboma |
Visual loss |
| Disease(s) Associated with SOX2 | |||||||||
| syndromic microphthalmia 3 |
| Mouse Phenotypes | vision/eye phenotype |
abnormal retina blood vessel morphology |
abnormal optic disk morphology |
optic nerve hypoplasia |
irregularly shaped pupil |
abnormal retina progenitor cell morphology |
abnormal eye size |
microphthalmia |
abnormal retina morphology |
disorganized retina layers |
retina hyperplasia |
retina hypoplasia |
anophthalmia |
|
| Availability | Mouse Genotype | |||||||||||||
| Sox2em1(IMPC)Mbp/Sox2+ | ||||||||||||||
| Sox2tm1Lpev/Sox2tm3Lpev | ||||||||||||||
| Sox2tm1Lpev/Sox2tm4Lpev | ||||||||||||||
| Sox2tm1Rlb/Sox2+ | * | |||||||||||||
| Sox2tm1.1Lan/Sox2tm1.1Lan Tg(Cryaa-cre)10Mlr/0 (conditional) |
* | |||||||||||||
| Sox2tm2Lpev/Sox2tm2Lpev Tg(Pax6-cre,GFP)2Pgr/? (conditional) |
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| Sox2tm1Lpev/Sox2tm2Lpev Tg(Pax6-cre,GFP)2Pgr/? (conditional) |
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| Sox2tm2Lpev/Sox2tm2.1Lpev Tg(Pax6-cre,GFP)2Pgr/? (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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