|
Symbol Name ID |
Sod1
superoxide dismutase 1, soluble MGI:98351 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Macroglossia |
Foot dorsiflexor weakness |
Lower limb muscle weakness |
Upper limb muscle weakness |
Gastroparesis |
Rigidity |
Spasticity |
Hypotonia |
Muscle spasm |
Muscle weakness |
Fatigable weakness of bulbar muscles |
Fatigable weakness of swallowing muscles |
Fatigable weakness of respiratory muscles |
Generalized muscle weakness |
Skeletal muscle atrophy |
Progressive distal muscular atrophy |
Progressive spinal muscular atrophy |
| Disease(s) Associated with SOD1 | |||||||||||||||||
| amyotrophic lateral sclerosis | |||||||||||||||||
| amyotrophic lateral sclerosis type 1 | |||||||||||||||||
| Down syndrome | |||||||||||||||||
| Parkinson's disease |
| Mouse Phenotypes | muscle phenotype |
myocardium necrosis |
decreased cardiac muscle contractility |
increased extensor digitorum longus weight |
increased quadriceps weight |
increased gastrocnemius weight |
increased soleus weight |
increased tibialis anterior weight |
abnormal muscle fiber morphology |
centrally nucleated skeletal muscle fibers |
increased skeletal muscle mass |
muscle degeneration |
abnormal muscle physiology |
abnormal muscle regeneration |
muscle weakness |
progressive muscle weakness |
|
| Availability | Mouse Genotype | ||||||||||||||||
| Sod1m1H/Sod1m1H | |||||||||||||||||
| Sod1tm1Dkd/Sod1tm1Dkd | |||||||||||||||||
| Tg(Sod1*G86R)M1Jwg/0 | |||||||||||||||||
| Sod1tm1Svb/Sod1tm1Svb Tg(ACTA1-cre)79Jme/0 (conditional) |
* | ||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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