Symbol Name ID |
Sod1
superoxide dismutase 1, soluble MGI:98351 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Decreased level of 1,5 anhydroglucitol in serum |
Hyperglycemia |
Diabetes mellitus |
Type II diabetes mellitus |
Hyperinsulinemia |
Insulin resistance |
Ketoacidosis |
Edema |
Pulmonary edema |
Disease(s) Associated with SOD1 | |||||||||
Down syndrome | |||||||||
newborn respiratory distress syndrome | |||||||||
retinitis pigmentosa | |||||||||
type 1 diabetes mellitus | |||||||||
type 2 diabetes mellitus |
Mouse Phenotypes | homeostasis/metabolism phenotype |
increased myocardial infarct size |
impaired adaptive thermogenesis |
increased circulating glucose level |
abnormal circulating hormone level |
increased circulating corticosterone level |
suppressed circulating follicle stimulating hormone level |
decreased circulating luteinizing hormone level |
decreased circulating insulin level |
decreased circulating leptin level |
decreased circulating triiodothyronine level |
increased circulating ketone body level |
increased circulating interleukin-6 level |
increased circulating tumor necrosis factor level |
abnormal energy expenditure |
abnormal enzyme/coenzyme level |
abnormal gas homeostasis |
increased oxygen consumption |
decreased respiratory quotient |
abnormal glucose homeostasis |
abnormal lipid homeostasis |
abnormal glycerol level |
enhanced lipolysis |
increased susceptibility to xenobiotic induced morbidity/mortality |
|
Availability | Mouse Genotype | ||||||||||||||||||||||||
Sod1tm1Dkd/Sod1tm1Dkd | |||||||||||||||||||||||||
Sod1tm1Leb/Sod1tm1Leb | |||||||||||||||||||||||||
Sod1tm1Ysh/Sod1tm1Ysh | |||||||||||||||||||||||||
Tg(Sod1*G86R)M1Jwg/0 | |||||||||||||||||||||||||
Sod1tm1Svb/Sod1tm1Svb Tg(ACTA1-cre)79Jme/0 (conditional) |
* |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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