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Symbol
Name
ID

Snap25
synaptosomal-associated protein 25
MGI:98331

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Type II diabetes mellitus
Disease(s) Associated with SNAP25	Type II diabetes mellitus
Down syndrome

Mouse Phenotypes

decreased glucagon secretion

abnormal insulin secretion

decreased insulin secretion

increased susceptibility to diet-induced obesity

hyperglycemia

decreased circulating ghrelin level

increased circulating insulin level

increased circulating leptin level

increased circulating cholesterol level

increased circulating triglyceride level

abnormal dopamine level

improved glucose tolerance

insulin resistance

abnormal serotonin level

Availability

Mouse Genotype

Snap25^tm1.1Bark/Snap25^tm1.1Bark

Snap25^tm1Mtaka/Snap25^tm1Mtaka

Snap25^Bdr/Snap25⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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