|
Symbol Name ID |
Shh
sonic hedgehog MGI:98297 |
| Darker colors indicate more annotations |
| Human Phenotypes | Iris coloboma |
Chorioretinal coloboma |
Optic atrophy |
Retinopathy |
Cyclopia |
Deeply set eye |
Hypertelorism |
Hypotelorism |
Proptosis |
Anophthalmia |
Microphthalmia |
Coloboma |
Ptosis |
| Disease(s) Associated with SHH | |||||||||||||
| holoprosencephaly | |||||||||||||
| holoprosencephaly 3 | |||||||||||||
| polydactyly | |||||||||||||
| solitary median maxillary central incisor |
| Mouse Phenotypes | abnormal retina ganglion cell morphology |
abnormal optic nerve morphology |
abnormal eye morphology |
abnormal eye development |
abnormal optic cup morphology |
abnormal optic stalk morphology |
abnormal optic vesicle formation |
cyclopia |
ocular hypertelorism |
microphthalmia |
abnormal eyelid morphology |
eyelids open at birth |
abnormal retina morphology |
|
| Availability | Mouse Genotype | |||||||||||||
| Shhtm1.1Rseg/Shhtm1.1Rseg | ||||||||||||||
| Shhtm1Chg/Shhtm1Chg | ||||||||||||||
| Shhtm3(cre)Chg/Shhtm3(cre)Chg | ||||||||||||||
| Shhtm1Amc/Shhtm1.1Rseg | ||||||||||||||
| Tg(KRT14-Shh)#Cobm/0 | ||||||||||||||
| Shhtm1(EGFP/cre)Cjt/Shhtm2Amc (conditional) | ||||||||||||||
| Shhtm1Amc/Shhtm2Amc Tg(KRT14-cre)1Amc/0 (conditional) |
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| Shhtm1Amc/Shhtm2Amc Tg(Thy1-cre)703Vaw/? (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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