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Symbol
Name
ID
Shh
sonic hedgehog
MGI:98297
Phenotype annotations related to embryo
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
embryo phenotype
abnormal neural crest cell apoptosis
abnormal neural crest cell migration
abnormal embryo development
abnormal dorsal-ventral axis patterning
embryonic growth retardation
decreased embryo size
abnormal neural tube morphology
absent floor plate
spina bifida
absent notochord
notochord degeneration
abnormal somite shape
decreased somite size
Availability Mouse Genotype
Shhtm1.1Rseg/Shhtm1.1Rseg *
Shhtm1Amc/Shhtm1Amc
Shhtm1Chg/Shhtm1Chg
Shhtm1Ptch/Shhtm1Ptch
Shhtm3(cre)Chg/Shhtm3(cre)Chg
Shhtm1Amc/Shhtm1.1Rseg *
Tg(KRT14-Shh)#Cobm/0
Shhtm1Chg/Shhtm2Amc
Nkx2-5tm1(cre)Rjs/Nkx2-5+  (conditional)
Shhtm1(EGFP/cre)Cjt/Shhtm2Amc  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory