About Help FAQ

Symbol
Name
ID

Scn4a
sodium channel, voltage-gated, type IV, alpha
MGI:98250

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Decreased activity of mitochondrial complex I	Abnormal blood potassium concentration	Hyperkalemia	Hypokalemia	Hyponatremia	Elevated circulating creatine kinase concentration	Mildly elevated creatine kinase	Nonimmune hydrops fetalis	Pleural effusion	Malignant hyperthermia	Ascites
Disease(s) Associated with SCN4A	Decreased activity of mitochondrial complex I	Abnormal blood potassium concentration	Hyperkalemia	Hypokalemia	Hyponatremia	Elevated circulating creatine kinase concentration	Mildly elevated creatine kinase	Nonimmune hydrops fetalis	Pleural effusion	Malignant hyperthermia	Ascites
congenital myopathy 22A
congenital myopathy 22B
hyperkalemic periodic paralysis
paramyotonia congenita of Von Eulenburg

Mouse Phenotypes		decreased circulating leptin level	decreased circulating alkaline phosphatase level	increased circulating amylase level	increased energy expenditure	improved glucose tolerance
Availability	Mouse Genotype	decreased circulating leptin level	decreased circulating alkaline phosphatase level	increased circulating amylase level	increased energy expenditure	improved glucose tolerance
	Scn4a^m1Aaa/Scn4a⁺
	Scn4a^{tm2b(KOMP)Wtsi}/Scn4a⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23