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Symbol
Name
ID
Raf1
v-raf-leukemia viral oncogene 1
MGI:97847
Phenotype annotations related to muscle
Darker colors indicate more annotations
Human Phenotypes
Aplasia/Hypoplasia of the abdominal wall musculature
Hypotonia
Muscle weakness
Disease(s) Associated with RAF1
Noonan syndrome

Mouse Phenotypes
increased myocardial fiber size
thin myocardium
dilated cardiomyopathy
decreased cardiac muscle contractility
decreased ventricle muscle contractility
increased cardiac muscle contractility
increased cardiomyocyte apoptosis
Availability Mouse Genotype
Raf1tm2.1Ara/Raf1tm2.1Ara
Raf1tm1.1Bgn/Raf1+
Raf1tm2Bacc/Raf1tm2Bacc
Tg(Myh6-cre)2182Mds/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory