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Symbol
Name
ID

Raf1
v-raf-leukemia viral oncogene 1
MGI:97847

Phenotype annotations related to craniofacial

Darker colors indicate more annotations

Human Phenotypes

Low posterior hairline

Dolichocephaly

Micrognathia

Mandibular prognathia

Macrocephaly

Abnormal facial shape

Triangular face

Midface retrusion

High forehead

Prominent forehead

Thick lower lip vermilion

Thick vermilion border

High palate

Wide mouth

Depressed nasal bridge

Sparse eyebrow

Downslanted palpebral fissures

Epicanthus

Disease(s) Associated with RAF1

Noonan syndrome

Noonan syndrome 5

Noonan syndrome with multiple lentigines 2

Mouse Phenotypes		abnormal cranium size	decreased cranium height	decreased cranium width	increased cranium width	abnormal facial morphology	flattened snout
Availability	Mouse Genotype	abnormal cranium size	decreased cranium height	decreased cranium width	increased cranium width	abnormal facial morphology	flattened snout
	Raf1^tm2.1Ara/Raf1^tm2.1Ara
	Raf1^tm1.1Bgn/Raf1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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