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Symbol
Name
ID

Rac2
Rac family small GTPase 2
MGI:97846

Phenotype annotations related to cellular

Darker colors indicate more annotations

Human Phenotypes	Decreased lymphocyte proliferation in response to anti-CD3	Decreased circulating IgG level	Decreased circulating total IgM	Partial absence of specific antibody response to Haemophilus influenzae type b (Hib) vaccine
Disease(s) Associated with RAC2	Decreased lymphocyte proliferation in response to anti-CD3	Decreased circulating IgG level	Decreased circulating total IgM
immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia
immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemia

Mouse Phenotypes		decreased vascular endothelial cell proliferation	abnormal granulocyte differentiation	impaired neutrophil chemotaxis	decreased T cell proliferation	oxidative stress
Availability	Mouse Genotype	decreased vascular endothelial cell proliferation	abnormal granulocyte differentiation	impaired neutrophil chemotaxis	decreased T cell proliferation	oxidative stress
	Rac2^tm1Mddw/Rac2^tm1Mddw
	Rac2^em1Shl/Rac2⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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