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Symbol Name ID |
Rac1
Rac family small GTPase 1 MGI:97845 |
| Darker colors indicate more annotations |
| Human Phenotypes | Echogenic intracardiac focus |
| Disease(s) Associated with RAC1 | |
| autosomal dominant intellectual developmental disorder 48 |
| Mouse Phenotypes | increased embryonic tissue cell apoptosis |
abnormal anterior visceral endoderm cell migration |
abnormal developmental patterning |
abnormal gastrulation |
abnormal germ layer development |
abnormal mesoderm development |
abnormal rostral-caudal axis patterning |
abnormal rostral-caudal body axis extension |
embryonic growth arrest |
decreased embryo size |
abnormal embryonic epiblast morphology |
thick embryonic epiblast |
abnormal notochordal plate morphology |
absent mesoderm |
abnormal neural tube closure |
abnormal primitive streak morphology |
abnormal primitive node morphology |
abnormal primitive streak formation |
impaired somite development |
absent somites |
abnormal embryonic-extraembryonic boundary morphology |
embryonic-extraembryonic boundary constriction |
abnormal extraembryonic endoderm formation |
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| Availability | Mouse Genotype | |||||||||||||||||||||||
| Rac1tm1Jms/Rac1tm1Jms | ||||||||||||||||||||||||
| Rac1tm2Tyb/Rac1tm2Tyb | ||||||||||||||||||||||||
| Rac1tm2Tyb/Rac1tm2Tyb Tg(Hhex-EGFP)#Rbe/0 |
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| Rac1tm1Tyb/Rac1tm2Tyb Edil3Tg(Sox2-cre)1Amc/Edil3+ (conditional) |
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| Rac1tm1Tyb/Rac1tm2Tyb Tg(Ttr-cre)1Hadj/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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