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Symbol
Name
ID

Pth
parathyroid hormone
MGI:97799

Phenotype annotations related to skeleton

Darker colors indicate more annotations

Human Phenotypes	Abnormal femoral metaphysis morphology	Abnormal tibial metaphysis morphology	Abnormal metaphysis morphology	Joint swelling	Pathologic fracture	Osteolysis	Osteosarcoma	Cerebral calcification
Disease(s) Associated with PTH	Abnormal femoral metaphysis morphology	Abnormal tibial metaphysis morphology	Abnormal metaphysis morphology	Joint swelling	Pathologic fracture	Osteolysis	Osteosarcoma	Cerebral calcification
familial isolated hypoparathyroidism
osteosarcoma

Mouse Phenotypes

increased osteocyte apoptosis

increased osteoblast apoptosis

abnormal cranium morphology

decreased osteoclast cell number

abnormal osteoclast morphology

short metacarpal bones

short metatarsal bones

increased width of hypertrophic chondrocyte zone

decreased length of long bones

small vertebral body

abnormal bone structure

increased bone mineral density

increased compact bone thickness

decreased osteoblast cell number

abnormal trabecular bone morphology

abnormal cartilage development

abnormal skeleton development

abnormal bone mineralization

Availability

Mouse Genotype

Pth^{tm1a(EUCOMM)Wtsi}/Pth^{tm1a(EUCOMM)Wtsi}

Pth^tm1Dgo/Pth^tm1Dgo

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23