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Symbol
Name
ID

Prnp
prion protein
MGI:97769

Phenotype annotations related to muscle

Darker colors indicate more annotations

Human Phenotypes	Lower limb muscle weakness	Rigidity	Extrapyramidal muscular rigidity	Spasticity	Generalized hypotonia	Frequent falls
Disease(s) Associated with PRNP	Lower limb muscle weakness	Rigidity	Extrapyramidal muscular rigidity	Spasticity	Generalized hypotonia	Frequent falls
Creutzfeldt-Jakob disease
Gerstmann-Straussler-Scheinker syndrome
Huntington's disease-like 1

Mouse Phenotypes		myoclonus	abnormal muscle fiber morphology	skeletal muscle fiber degeneration	abnormal skeletal muscle morphology	abnormal skeletal muscle fiber type ratio	muscle degeneration	muscular atrophy	abnormal muscle physiology	myopathy
Availability	Mouse Genotype	myoclonus	abnormal muscle fiber morphology	skeletal muscle fiber degeneration	abnormal skeletal muscle morphology	abnormal skeletal muscle fiber type ratio	muscle degeneration	muscular atrophy	abnormal muscle physiology	myopathy
	Prnp^tm1Cwe/Prnp^tm1Cwe Tg(Prnp*)#Rgab/0
	Prnp^tm1Cwe/Prnp^tm1Cwe Tg(PrnpS170NN174T)1020Aag/0
	Prnp^tm2.1Cwe/Prnp^tm2.1Cwe
	Tg(Prnp*)#Rgab/0
	Tg(Prnp*P101L)2866Sbp/0

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23