|
Symbol Name ID |
Pparg
peroxisome proliferator activated receptor gamma MGI:97747 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Splenomegaly |
Hepatosplenomegaly |
Hepatomegaly |
Peritoneal abscess |
Increased waist to hip ratio |
Increased body mass index |
Small for gestational age |
Weight loss |
Obesity |
Intrauterine growth retardation |
| Disease(s) Associated with PPARG | ||||||||||
| familial partial lipodystrophy type 3 | ||||||||||
| obesity | ||||||||||
| pancreatic cancer | ||||||||||
| pre-eclampsia | ||||||||||
| type 2 diabetes mellitus |
| Mouse Phenotypes | decreased body fat mass |
heart right ventricle hypertrophy |
cardiac hypertrophy |
embryonic growth retardation |
decreased embryo size |
pancreas hyperplasia |
growth/size/body region phenotype |
decreased body mass index |
decreased lean body mass |
decreased body weight |
slow postnatal weight gain |
abnormal body weight |
decreased susceptibility to diet-induced obesity |
postnatal growth retardation |
enlarged kidney |
increased kidney weight |
enlarged liver |
increased liver weight |
enlarged spleen |
|
| Availability | Mouse Genotype | |||||||||||||||||||
| Ppargm1Btlr/Ppargm1Btlr | ||||||||||||||||||||
| Ppargtm1.1Auw/Ppargtm1.1Auw | ||||||||||||||||||||
| Ppargtm1Auw/Ppargtm1Auw | ||||||||||||||||||||
| Ppargtm1Lja/Ppargtm1Lja | ||||||||||||||||||||
| Ppargtm1Tka/Ppargtm1Tka | ||||||||||||||||||||
| Ppargtm1Yec/Ppargtm1Yec | ||||||||||||||||||||
| Ppargtm1Avp/Pparg+ | * | |||||||||||||||||||
| Ppargtm1b(KOMP)Wtsi/Pparg+ | ||||||||||||||||||||
| Ppargtm1Lja/Pparg+ | ||||||||||||||||||||
| Ppargtm1Tka/Pparg+ | ||||||||||||||||||||
| Ppargtm1Uls/Pparg+ | ||||||||||||||||||||
| Ppargtm2(tTA)Yba/Pparg+ | ||||||||||||||||||||
| Ppargtm3(tTA)Yba/Pparg+ | ||||||||||||||||||||
| Ppargtm1.1Gonz/Ppargtm1.1Gonz (conditional) | ||||||||||||||||||||
| Ppargtm1.1Gonz/Ppargtm1.1Gonz Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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| Ppargtm1.1Gonz/Ppargtm1.1Gonz Tg(Aqp2-cre)1Dek/0 (conditional) |
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| Ppargtm2Rev/Ppargtm2Rev Tg(Fabp4-cre)1Rev/0 (conditional) |
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| Ppargtm2Rev/Ppargtm2Rev Tg(Tek-cre)1Ywa/? (conditional) |
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| Ppargtm2Rev/Ppargtm2Rev Tg(Tek-cre)12Flv/? (conditional) |
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| Ppargtm2Rev/Ppargtm2Rev Tg(Tagln-cre)1Her/? (conditional) |
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| Ppargtm2Rev/Ppargtm2Rev Tg(Camk2a-cre)62Jzt/? (conditional) |
* | |||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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