Symbol
Name
ID

Pkd1
polycystin 1, transient receptor potential channel interacting
MGI:97603

Phenotype annotations related to cellular

Darker colors indicate more annotations

Mouse Phenotypes

increased kidney epithelial cell primary cilium length

abnormal peroxisome morphology

abnormal mitotic spindle morphology

increased kidney apoptosis

increased renal tubule apoptosis

abnormal osteoblast differentiation

impaired osteoblast differentiation

decreased chondrocyte proliferation

increased kidney cell proliferation

increased osteoblast proliferation

increased cell proliferation

increased hepatocyte proliferation

abnormal kidney epithelial cell primary cilium physiology

decreased fatty acid oxidation

oxidative stress

Availability

Mouse Genotype

Pkd1^tm1Jzh/Pkd1^tm1Jzh

Pkd1^tm1.2Djmp/Pkd1⁺

Pkd1^tm1Shh/Pkd1^tm1.1Pcha

Tg(Pkd1)6Mtru/0

Tg(Pkd1)26Mtru/0

Pkd1^tm2Ggg/Pkd1^tm2Ggg
Tg(Nes-cre)Wme/0 (conditional)

Pkd1^tm2Ggg/Pkd1^tm2Ggg
Tg(Col1a1-cre)1Bek/0 (conditional)

Pkd1^tm2Ggg/Pkd1^tm2Ggg
Tg(Hoxb7-cre)13Amc/0 (conditional)

Pkd1^tm2Som/Pkd1^tm2Som
Tg(Cdh16-cre)91Igr/0 (conditional)

Pkd1^tm3Jzh/Pkd1^tm3Jzh
Tg(Ggt1-cre)M3Egn/0 (conditional)

Pkd1^tm3Jzh/Pkd1^tm3Jzh
H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ (conditional)

Pkd1^tm3Jzh/Pkd1^tm3Jzh (conditional)

Pkd1^tm1.1Djmp/Pkd1^tm1.2Djmp
Tg(Cdh16-cre/ERT2)F427Djmp/0 (conditional)

Pkd1^tm1.1Pcha/Pkd1^tm2Som
Tg(Cdh16-cre)91Igr/0 (conditional)

Pkd1^tm1Som/Pkd1^tm2Som
Tg(Cdh16-cre/ERT2)24Igr/? (conditional)

Pkd1^tm2Ggg/Pkd1⁺
Tg(Col1a1-cre)1Bek/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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