Symbol Name ID |
Prf1
perforin 1 (pore forming protein) MGI:97551 |
! | Indicates phenotype varies with strain background. |
Darker colors indicate more annotations |
Human Phenotypes | Lymphoma |
Disease(s) Associated with PRF1 | |
non-Hodgkin lymphoma |
Mouse Phenotypes | increased T cell derived lymphoma incidence |
abnormal tumor morphology |
increased tumor growth/size |
increased lymphoma incidence |
increased B cell derived lymphoma incidence |
increased lung adenocarcinoma incidence |
increased sarcoma incidence |
increased incidence of induced tumors |
decreased tumor latency |
increased tumor latency |
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Availability | Mouse Genotype | ||||||||||
Prf1tm1Sdz/Prf1tm1Sdz | ! | ||||||||||
Prf1tm1Tsc/Prf1tm1Tsc | |||||||||||
Prf1tm1Sdz/Prf1+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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