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Symbol
Name
ID

Pfkm
phosphofructokinase, muscle
MGI:97548

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Increased total bilirubin	Hyperuricemia	Elevated circulating creatine kinase concentration	Elevated circulating aldolase concentration	Increased circulating lactate dehydrogenase concentration	Reduced muscle 6-phosphofructokinase activity	Increased muscle glycogen content	Hematuria	Exercise-induced myoglobinuria	Exercise intolerance
Disease(s) Associated with PFKM
glycogen storage disease VII

Mouse Phenotypes

impaired exercise endurance

increased cardiac muscle glycogen level

decreased insulin secretion

increased circulating bilirubin level

increased circulating glucose level

decreased circulating insulin level

decreased circulating lactate level

increased lactate dehydrogenase level

hypoxia

abnormal glucose homeostasis

impaired glucose tolerance

increased skeletal muscle glycogen level

Availability

Mouse Genotype

Pfkm^{GT(OST56064)Lex}/Pfkm^{GT(OST56064)Lex}

Pfkm^tm1Fbos/Pfkm^tm1Fbos

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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