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Symbol Name ID |
Pcsk2
proprotein convertase subtilisin/kexin type 2 MGI:97512 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Type II diabetes mellitus |
Insulin resistance |
| Disease(s) Associated with PCSK2 | ||
| type 2 diabetes mellitus |
| Mouse Phenotypes | homeostasis/metabolism phenotype |
decreased glucagon secretion |
decreased insulin secretion |
decreased circulating glucose level |
decreased circulating glucagon level |
decreased circulating insulin level |
increased circulating insulin level |
increased circulating HDL cholesterol level |
increased circulating cholesterol level |
increased circulating iron level |
increased circulating alanine transaminase level |
increased circulating amylase level |
impaired glucose tolerance |
improved glucose tolerance |
decreased pituitary hormone level |
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| Availability | Mouse Genotype | |||||||||||||||
| Pcsk2em1(IMPC)H/Pcsk2em1(IMPC)H | ||||||||||||||||
| Pcsk2tm1Dfs/Pcsk2tm1Dfs | * | |||||||||||||||
| Pcsk2em1(IMPC)H/Pcsk2+ | ||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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