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Symbol Name ID |
Pck1
phosphoenolpyruvate carboxykinase 1, cytosolic MGI:97501 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Type II diabetes mellitus |
Insulin resistance |
| Disease(s) Associated with PCK1 | ||
| type 2 diabetes mellitus |
| Mouse Phenotypes | homeostasis/metabolism phenotype |
abnormal circulating amino acid level |
increased circulating ammonia level |
increased blood urea nitrogen level |
decreased circulating glucose level |
hypoglycemia |
hyperglycemia |
decreased circulating ketone body level |
increased circulating ketone body level |
increased circulating lactate level |
abnormal circulating lipid level |
increased circulating free fatty acids level |
decreased circulating triglyceride level |
increased circulating triglyceride level |
decreased liver glycogen level |
decreased liver triglyceride level |
increased liver triglyceride level |
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| Availability | Mouse Genotype | |||||||||||||||||
| Pck1tm1.1Lre/Pck1tm1.1Lre | * | |||||||||||||||||
| Pck1tm1.2Mgn/Pck1tm1.2Mgn | ||||||||||||||||||
| Pck1tm1Rwh/Pck1tm1Rwh | ||||||||||||||||||
| Pck1tm1.1Mgn/Pck1tm1.1Mgn Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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