Symbol
Name
ID

Pax9
paired box 9
MGI:97493

Phenotype annotations related to skeleton

Darker colors indicate more annotations

Human Phenotypes	Aplasia of the maxilla	Enamel hypoplasia
Disease(s) Associated with PAX9	Aplasia of the maxilla	Enamel hypoplasia
tooth agenesis

Mouse Phenotypes

abnormal cranium morphology

abnormal pterygoid process morphology

abnormal hyoid bone morphology

abnormal hyoid bone greater horn morphology

abnormal hyoid bone lesser horn morphology

absent alveolar process

abnormal tooth morphology

absent incisors

absent lower incisors

abnormal molar morphology

decreased molar number

absent molars

abnormal tooth development

abnormal dentin development

abnormal ameloblast morphology

failure of tooth eruption

arrest of tooth development

growth retardation of molars

abnormal dentin morphology

absent enamel

abnormal tooth attrition

decreased tooth number

absent teeth

abnormal mandible morphology

absent mandibular coronoid process

abnormal maxillary shelf morphology

absent maxillary shelf

absent premaxilla

abnormal palatine bone horizontal plate morphology

absent palatine bone horizontal plate

abnormal Reichert's cartilage morphology

absent Reichert cartilage

abnormal tendon morphology

abnormal laryngeal cartilage morphology

abnormal thyroid cartilage morphology

abnormal inferior horn of thyroid cartilage morphology

abnormal superior horn of thyroid cartilage morphology

fused tracheal cartilage rings

Availability

Mouse Genotype

Pax9^tm1Hpt/Pax9^tm1Hpt

Pax9^tm1Rbal/Pax9^tm1Rbal

Pax9^tm1Hpt/Pax9^tm1Rbal

Pax9^tm1.1Hpt/Pax9^tm1.1Hpt
Tg(Pgk1-cre)1Lni/? (conditional)

Pax9^tm1.1Hpt/Pax9^tm1.1Hpt
H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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