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Symbol
Name
ID
Pax8
paired box 8
MGI:97492
Phenotype annotations related to hearing/vestibular/ear
Darker colors indicate more annotations

Mouse Phenotypes
abnormal stapedial artery morphology
absent stapedial artery
abnormal kinocilium morphology
absent round window
decreased round window size
abnormal middle ear ossicle morphology
abnormal stapes morphology
abnormal stapes crus morpholgy
abnormal outer ear morphology
abnormal external auditory canal morphology
external auditory canal stenosis
absent outer ear
delayed ear emergence
small ears
abnormal auditory bulla morphology
delayed inner ear development
abnormal cochlear hair cell morphology
abnormal cochlear hair cell stereociliary bundle morphology
abnormal outer hair cell stereociliary bundle morphology
abnormal cochlear IHC efferent innervation pattern
abnormal inner hair cell synaptic ribbon morphology
cochlear outer hair cell degeneration
abnormal organ of Corti morphology
abnormal pillar cell morphology
enlarged tectorial membrane
abnormal middle ear morphology
abnormal cochlear inner hair cell physiology
increased or absent threshold for auditory brainstem response
deafness
Availability Mouse Genotype
Pax8tm1Pgr/Pax8tm1Pgr
Pax8tm1Rdl/Pax8tm1.1(cre)Mbu  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory