About Help FAQ

Symbol
Name
ID

Pax8
paired box 8
MGI:97492

Phenotype annotations related to craniofacial

Darker colors indicate more annotations

Human Phenotypes	Large posterior fontanelle	Macroglossia
Disease(s) Associated with PAX8	Large posterior fontanelle	Macroglossia
congenital nongoitrous hypothyroidism 2

Mouse Phenotypes

absent round window

decreased round window size

abnormal middle ear ossicle morphology

abnormal stapes morphology

abnormal stapes crus morpholgy

abnormal outer ear morphology

abnormal external auditory canal morphology

external auditory canal stenosis

absent outer ear

delayed ear emergence

small ears

Availability

Mouse Genotype

Pax8^tm1Pgr/Pax8^tm1Pgr

Pax8^tm1Rdl/Pax8^{tm1.1(cre)Mbu} (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23