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Symbol
Name
ID

Otx2
orthodenticle homeobox 2
MGI:97451

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Hypoglycemia	Decreased circulating ACTH concentration
Disease(s) Associated with OTX2	Hypoglycemia	Decreased circulating ACTH concentration
panhypopituitarism

Mouse Phenotypes		decreased susceptibility to dopaminergic neuron neurotoxicity	increased susceptibility to dopaminergic neuron neurotoxicity	decreased circulating luteinizing hormone level
Availability	Mouse Genotype			decreased circulating luteinizing hormone level
	Otx2^tm1Pas/Otx2⁺
	Gt(ROSA)26Sor^{tm1.1(Otx2)Daac}/Gt(ROSA)26Sor^{tm1.1(Otx2)Daac} Slc6a3^{tm1.1(cre)Bkmn}/Slc6a3⁺ (conditional)
	Gt(ROSA)26Sor^{tm1.1(Otx2)Daac}/Gt(ROSA)26Sor⁺ Slc6a3^{tm1.1(cre)Bkmn}/Slc6a3⁺ (conditional)
	Otx2^tm6Asim/Otx2^tm11Asim Slc6a3^{tm1.1(cre)Bkmn}/Slc6a3⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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