Symbol
Name
ID

Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
MGI:97384

Phenotype annotations related to behavior/neurological

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Feeding difficulties	Lack of spontaneous play	Impaired ability to form peer relationships	Autism	Inflexible adherence to routines	Motor stereotypy	Restrictive behavior
Disease(s) Associated with NTRK2	Feeding difficulties	Lack of spontaneous play	Impaired ability to form peer relationships	Autism	Inflexible adherence to routines	Motor stereotypy	Restrictive behavior
autistic disorder
developmental and epileptic encephalopathy 58

Mouse Phenotypes

behavior/neurological phenotype

enhanced behavioral response to cocaine

abnormal learning/memory/conditioning

abnormal avoidance learning behavior

abnormal contextual conditioning behavior

abnormal spatial learning

abnormal spatial working memory

absent suckling reflex

no swallowing reflex

increased thigmotaxis

abnormal response to novel object

impaired righting response

abnormal pupillary reflex

abnormal vibrissae reflex

abnormal gait

increased locomotor activity

hyperactivity

induced hyperactivity

abnormal circadian behavior

decreased kindling response

Availability

Mouse Genotype

Ntrk2^tm1.1Tes/Ntrk2^tm1.1Tes

Ntrk2^tm1Bbd/Ntrk2^tm1Bbd

Ntrk2^tm1Kln/Ntrk2^tm1Kln

Ntrk2^tm1Rohr/Ntrk2^tm1Rohr

Ntrk2^tm2.1Tes/Ntrk2^tm2.1Tes

Ntrk2^tm1.1Tes/Ntrk2⁺

Ntrk2^tm1Mini/Ntrk2⁺

Ntrk2^tm1Jom/Ntrk2^tm1Jom
Tg(Syn1-cre)671Jxm/0 (conditional)

Ntrk2^tm2Kln/Ntrk2^tm2Kln
Tg(Nes-cre)1Kln/0 (conditional)

Ntrk2^tm2Kln/Ntrk2^tm2Kln
Tg(Penk-cre,-lacZ)1Mini/0 (conditional)

Ntrk2^tm2Kln/Ntrk2^tm2Kln
Tg(Cck-cre,-lacZ)1Mini/0 (conditional)

Ntrk2^tm1Bbd/Ntrk2^tm2Kln
Tg(Camk2a-cre)159Kln/0 (conditional)

Ntrk2^tm1Jom/Ntrk2⁺
Tg(Syn1-cre)671Jxm/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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