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Symbol
Name
ID
Nras
neuroblastoma ras oncogene
MGI:97376
Phenotype annotations related to craniofacial
Darker colors indicate more annotations
Human Phenotypes
Low posterior hairline
Frontal bossing
Prominent occiput
Biparietal narrowing
Cranial asymmetry
Plagiocephaly
Prominence of the premaxilla
Dandy-Walker malformation
Macrocephaly
Facial asymmetry
Round face
Full cheeks
Adenoma sebaceum
Broad forehead
High forehead
Prominent forehead
Everted lower lip vermilion
Deep philtrum
Long philtrum
Open mouth
Abnormal dental morphology
Abnormality of dental color
Anteverted nares
Narrow nasal ridge
Broad nasal tip
Depressed nasal bridge
Wide nasal bridge
Short nose
Long eyebrows
Downslanted palpebral fissures
Epicanthus
Telecanthus
Periorbital fullness
Disease(s) Associated with NRAS
large congenital melanocytic nevus
linear nevus sebaceous syndrome
Noonan syndrome 6

Mouse Phenotypes
abnormal cranium morphology
Availability Mouse Genotype
Nrastm1Tyj/Nrastm1Tyj
Tg(Tyr-cre)1Lru/0  (conditional)
Nrastm1Tyj/Nras+
Tg(Tyr-cre)1Lru/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory