|
Symbol Name ID |
Nos2
nitric oxide synthase 2, inducible MGI:97361 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Hyperbilirubinemia |
Elevated circulating C-reactive protein concentration |
Type II diabetes mellitus |
Insulin resistance |
Fever |
| Disease(s) Associated with NOS2 | |||||
| malaria | |||||
| type 2 diabetes mellitus |
| Mouse Phenotypes | homeostasis/metabolism phenotype |
increased myocardial infarct size |
abnormal platelet physiology |
abnormal platelet aggregation |
abnormal homeostasis |
increased circulating creatinine level |
abnormal blood homeostasis |
abnormal circulating glucose level |
hyperglycemia |
increased circulating antidiuretic hormone level |
abnormal circulating estradiol level |
increased circulating prolactin level |
decreased circulating insulin level |
decreased circulating leptin level |
increased circulating ketone body level |
increased circulating cholesterol level |
increased circulating triglyceride level |
increased circulating VLDL triglyceride level |
decreased circulating alanine transaminase level |
decreased circulating aspartate transaminase level |
abnormal circulating serum albumin level |
abnormal blood coagulation |
abnormal enzyme/coenzyme level |
abnormal nitric oxide homeostasis |
abnormal glucose homeostasis |
improved glucose tolerance |
abnormal glycogen homeostasis |
decreased liver glycogen level |
increased urine glucose level |
increased insulin sensitivity |
abnormal hormone level |
decreased adiponectin level |
abnormal adrenocorticotropin level |
increased liver triglyceride level |
increased triglyceride level |
increased urine pH |
decreased urine prostaglandin level |
albuminuria |
ketoaciduria |
increased renin activity |
increased mortality induced by ionizing radiation |
decreased cerebral infarct size |
decreased susceptibility to kidney reperfusion injury |
abnormal bone healing |
delayed wound healing |
enhanced wound healing |
decreased susceptibility to injury |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||||||||
| Nos2tm1Lau/Nos2tm1Lau | * | |||||||||||||||||||||||||||||||||||||||||||||||
| Nos2tm1Mrl/Nos2tm1Mrl | * | |||||||||||||||||||||||||||||||||||||||||||||||
| Tg(Ins2-Nos2)31Okam/0 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Tg(Ins2-Nos2)40Okam/0 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Tg(Alb-Nos2)1Mkan/? | ||||||||||||||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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