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Symbol Name ID |
Myc
myelocytomatosis oncogene MGI:97250 |
| Darker colors indicate more annotations |
| Human Phenotypes | Bruising susceptibility |
Purpura |
Ecchymosis |
Petechiae |
Breast carcinoma |
| Disease(s) Associated with MYC | |||||
| acute promyelocytic leukemia | |||||
| breast cancer |
| Mouse Phenotypes | abnormal mammary gland morphology |
abnormal mammary gland development |
abnormal branching of the mammary ductal tree |
abnormal involution of the mammary gland |
mammary gland duct hyperplasia |
abnormal mammary gland lobule morphology |
abnormal mammary gland alveolus morphology |
mammary gland alveolar hyperplasia |
increased mammary gland tumor incidence |
increased mammary adenocarcinoma incidence |
mammary gland hyperplasia |
lactation failure |
abnormal mammary gland epithelium physiology |
increased mammary gland apoptosis |
belly spot |
variable body spotting |
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| Availability | Mouse Genotype | ||||||||||||||||
| Tg(MMTV-Myc)WT13Jrn/0 | |||||||||||||||||
| Tg(MMTV-Myc)WT21Jrn/0 | |||||||||||||||||
| Tg(MMTV-Myc*T58A)TA14Jrn/0 | |||||||||||||||||
| Tg(MMTV-Myc*T58A)TA39Jrn/0 | |||||||||||||||||
| Tg(MMTV-Myc*T58A)TA41Jrn/0 | |||||||||||||||||
| Tg(WapMyc)212Bri/0 | |||||||||||||||||
| Gt(ROSA)26Sortm1(Myc)Rcse/Gt(ROSA)26Sortm1(Myc)Rcse Tg(Wap-cre)11738Mam/0 (conditional) |
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| Gt(ROSA)26Sortm2(myc*T58A)Rcse/Gt(ROSA)26Sortm2(myc*T58A)Rcse Tg(Wap-cre)11738Mam/0 (conditional) |
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| Gt(ROSA)26Sortm3(myc*S62A)Rcse/Gt(ROSA)26Sortm3(myc*S62A)Rcse Tg(Wap-cre)11738Mam/0 (conditional) |
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| Myctm2Fwa/Myctm2Fwa H2az2Tg(Wnt1-cre)11Rth/H2az2+ (conditional) |
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| Myctm2Fwa/Myc+ H2az2Tg(Wnt1-cre)11Rth/H2az2+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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