Symbol Name ID |
Msx2
msh homeobox 2 MGI:97169 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Low anterior hairline |
Single transverse palmar crease |
Hyperextensible skin |
Minimal subcutaneous fat |
Aplasia cutis congenita of scalp |
Disease(s) Associated with MSX2 | |||||
craniosynostosis | |||||
parietal foramina |
Mouse Phenotypes | integument phenotype |
abnormal mammary gland embryonic development |
abnormal coat/ hair morphology |
alopecia |
focal hair loss |
premature hair loss |
short hair |
abnormal hair shaft morphology |
abnormal nail morphology |
abnormal nail matrix morphology |
deformed nails |
long nails |
long toenails |
abnormal hair follicle morphology |
abnormal hair follicle bulb morphology |
abnormal hair follicle matrix region morphology |
disorganized matrix sheath cells |
abnormal hair follicle inner root sheath morphology |
disorganized inner root sheath cells |
abnormal hair follicle orientation |
disorganized outer root sheath cells |
thin hair follicle outer root sheath |
distorted hair follicle pattern |
curly vibrissae |
short vibrissae |
abnormal hair shedding |
delayed hair regrowth |
abnormal skin morphology |
abnormal dermal layer morphology |
dermis papillary layer hypercellularity |
abnormal epidermal layer morphology |
abnormal epidermis stratum basale morphology |
hyperkeratosis |
disorganized suprabasal layer |
thick epidermis suprabasal layer |
epidermal desquamation |
thick epidermis |
flaky skin |
scaly skin |
thick skin |
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Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||||||
Msx2m1Btlr/Msx2m1Btlr | |||||||||||||||||||||||||||||||||||||||||
Msx2tm1.1Yvla/Msx2tm1.1Yvla | |||||||||||||||||||||||||||||||||||||||||
Msx2tm1Rilm/Msx2tm1Rilm | * | ||||||||||||||||||||||||||||||||||||||||
Tg(Msx2)1Rem/0 | |||||||||||||||||||||||||||||||||||||||||
Msx2tm1Rem/Msx2tm1Rem Tg(Msx2-cre)5Rem/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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