Symbol
Name
ID

Mc3r
melanocortin 3 receptor
MGI:96929

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Decreased resting energy expenditure
Disease(s) Associated with MC3R	Decreased resting energy expenditure
obesity

Mouse Phenotypes

homeostasis/metabolism phenotype

increased susceptibility to diet-induced obesity

increased circulating insulin level

abnormal circulating leptin level

increased circulating leptin level

increased circulating resistin level

decreased circulating triglyceride level

abnormal energy homeostasis

decreased energy expenditure

abnormal respiratory quotient

decreased respiratory quotient

Availability

Mouse Genotype

Mc3r^tm1Butl/Mc3r^tm1Butl

Mc3r^tm1Cone/Mc3r^tm1Cone

Mc3r^tm1Lvp/Mc3r^tm1Lvp

Mc3r^tm1Butl/Mc3r^tm1Butl
Tg(Nr5a1-cre)2Lowl/0 (conditional)

Mc3r^tm1Butl/Mc3r^tm1Butl
Tg(Nes-cre)1Kln/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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