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Symbol
Name
ID
Mc3r
melanocortin 3 receptor
MGI:96929
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Decreased resting energy expenditure
Disease(s) Associated with MC3R
obesity

Mouse Phenotypes
homeostasis/metabolism phenotype
increased susceptibility to diet-induced obesity
increased circulating insulin level
abnormal circulating leptin level
increased circulating leptin level
decreased circulating triglyceride level
abnormal energy homeostasis
decreased energy expenditure
abnormal respiratory quotient
decreased respiratory quotient
Availability Mouse Genotype
Mc3rtm1Butl/Mc3rtm1Butl
Mc3rtm1Cone/Mc3rtm1Cone
Mc3rtm1Lvp/Mc3rtm1Lvp
Mc3rtm1Butl/Mc3rtm1Butl
Tg(Nr5a1-cre)2Lowl/0  (conditional)
*
Mc3rtm1Butl/Mc3rtm1Butl
Tg(Nes-cre)1Kln/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory