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Symbol
Name
ID
Lef1
lymphoid enhancer binding factor 1
MGI:96770
Phenotype annotations related to integument
Darker colors indicate more annotations
Human Phenotypes
Breast carcinoma
Disease(s) Associated with LEF1
ovarian cancer

Mouse Phenotypes
absent subcutaneous adipose tissue
abnormal mammary gland bud morphology
absent mammary gland
epithelioid cyst
absent hair follicle melanin granules
alopecia
abnormal hair follicle morphology
abnormal hair follicle development
underdeveloped hair follicles
abnormal hair follicle orientation
decreased hair follicle number
absent vibrissae
sparse vibrissae
abnormal skin condition
thick skin
thin skin
increased skin tumor incidence
Availability Mouse Genotype
Lef1tm1Rug/Lef1tm1Rug
Tg(Krt14-dnLef1)LFmw/?

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory