Symbol Name ID |
Lef1
lymphoid enhancer binding factor 1 MGI:96770 |
Darker colors indicate more annotations |
Human Phenotypes | Breast carcinoma |
Disease(s) Associated with LEF1 | |
ovarian cancer |
Mouse Phenotypes | absent subcutaneous adipose tissue |
abnormal mammary gland bud morphology |
absent mammary gland |
epithelioid cyst |
absent hair follicle melanin granules |
alopecia |
abnormal hair follicle morphology |
abnormal hair follicle development |
underdeveloped hair follicles |
abnormal hair follicle orientation |
decreased hair follicle number |
absent vibrissae |
sparse vibrissae |
abnormal skin condition |
thick skin |
thin skin |
increased skin tumor incidence |
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Availability | Mouse Genotype | |||||||||||||||||
Lef1tm1Rug/Lef1tm1Rug | ||||||||||||||||||
Tg(Krt14-dnLef1)LFmw/? |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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