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Symbol
Name
ID
L1cam
L1 cell adhesion molecule
MGI:96721
Phenotype annotations related to behavior/neurological
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Abdominal pain
Anorexia
Poor appetite
Back pain
Negativism
Chronic fatigue
Disease(s) Associated with L1CAM
pancreatic cancer
schizophrenia

Mouse Phenotypes
behavior/neurological phenotype
abnormal behavioral response to light
increased exploration in new environment
abnormal spatial learning
decreased anxiety-related response
increased thigmotaxis
increased grooming behavior
abnormal motor capabilities/coordination/movement
abnormal response to tactile stimuli
impaired coordination
impaired limb coordination
decreased grip strength
increased vertical activity
decreased locomotor activity
hyperactivity
hindlimb paralysis
abnormal thermal nociception
abnormal social/conspecific interaction behavior
abnormal social investigation
Availability Mouse Genotype
L1camtm1(tTA)Msch/L1cam+ *
L1camtm1Mtei/Y
L1camtm1Sor/Y
L1camtm2.1Vlem/Y *
L1camtm3.1Vlem/Y *
L1camtm4.1Vlem/Y *
L1camtm1Fmo/Y
Tg(Camk2a-cre)1Gsc/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory