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Symbol
Name
ID

Krt14
keratin 14
MGI:96688

Phenotype annotations related to integument

Darker colors indicate more annotations

Human Phenotypes

Alopecia of scalp

Oral mucosal blisters

Palmoplantar hyperkeratosis

Palmoplantar keratoderma

Punctate palmoplantar hyperkeratosis

Decreased number of sweat glands

Dystrophic toenail

Malalignment of the great toenail

Subungual hyperkeratosis

Fragile nails

Ridged nail

Nail dystrophy

Onychogryposis

Onycholysis

Anhidrosis

Hypohidrosis

Abnormal blistering of the skin

Acral blistering

Stratum basale cleavage

Abnormal dermoepidermal hemidesmosome morphology

Generalized reticulate brown pigmentation

Hyperpigmentation in sun-exposed areas

Reticular hyperpigmentation

Hypopigmentation of the skin

Reticulated skin pigmentation

Dry skin

Atrophic scars

Milia

Adermatoglyphia

Disease(s) Associated with KRT14

dermatopathia pigmentosa reticularis

epidermolysis bullosa simplex

Naegeli-Franceschetti-Jadassohn syndrome

Mouse Phenotypes		abnormal keratinocyte apoptosis	abnormal epidermal layer morphology	abnormal epidermis stratum basale morphology	abnormal epidermis stratum corneum morphology	abnormal keratinocyte morphology	blistering	increased skin papilloma incidence
Availability	Mouse Genotype	abnormal keratinocyte apoptosis	abnormal epidermal layer morphology	abnormal epidermis stratum basale morphology	abnormal epidermis stratum corneum morphology	abnormal keratinocyte morphology	blistering	increased skin papilloma incidence
	Krt14^{tm1(Krt10)Pko}/Krt14^{tm1(Krt10)Pko}
	Krt14^tm1Der/Krt14^tm1Der
	Krt14^tm1Efu/Krt14^tm1Efu
	Krt14^tm2Der/Krt14⁺
	Krt14^tm1Der/Krt14⁺ Tg(KRT14-cre/PGR)1Der/? (conditional)
	Krt14^tm1Der/Krt14⁺ Tg(KRT5-cre/PGR)1Der/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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