About Help FAQ

Symbol
Name
ID

Jup
junction plakoglobin
MGI:96650

Phenotype annotations related to integument

*	Aspects of the system are reported to show a normal phenotype.
!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Human Phenotypes

Sparse scalp hair

Sparse eyebrow

Diffuse palmoplantar hyperkeratosis

Palmoplantar keratoderma

Breast carcinoma

Sparse body hair

Abnormality of hair texture

Curly hair

Woolly hair

Subungual hyperkeratosis

Nail dystrophy

Onycholysis

Hyperhidrosis

Abnormal blistering of the skin

Acantholysis

Epidermal acanthosis

Fragile skin

Acanthosis nigricans

Hyperkeratosis

Disease(s) Associated with JUP

arrhythmogenic right ventricular dysplasia 12

Naxos disease

ovarian cancer

Mouse Phenotypes

integument phenotype

impaired skin barrier function

abnormal epidermal layer morphology

absent epidermis stratum corneum

abnormal epidermis stratum granulosum morphology

abnormal epidermis stratum spinosum morphology

acantholysis

thin epidermis

blistering

loose skin

pallor

wrinkled skin

abnormal skin physiology

decreased skin tensile strength

Availability

Mouse Genotype

Jup^tm1.1Chen/Jup^tm1.1Chen

Jup^tm1Kem/Jup^tm1Kem

*!

Jup^tm1Ruiz/Jup^tm1Ruiz

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23