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Symbol
Name
ID

Insr
insulin receptor
MGI:96575

Phenotype annotations related to growth/size/body

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Hepatomegaly	Abdominal distention	Abnormality of the abdominal wall	Increased waist to hip ratio	Decreased body weight	Failure to thrive	Severe failure to thrive	Intrauterine growth retardation	Severe intrauterine growth retardation	Postnatal growth retardation
Disease(s) Associated with INSR	Hepatomegaly	Abdominal distention	Abnormality of the abdominal wall	Increased waist to hip ratio	Decreased body weight	Failure to thrive	Severe failure to thrive	Intrauterine growth retardation	Severe intrauterine growth retardation	Postnatal growth retardation
Donohue syndrome
type 2 diabetes mellitus

Mouse Phenotypes		enlarged gallbladder	growth/size/body region phenotype	abnormal lean body mass	decreased body weight	increased body weight	postnatal growth retardation	enlarged liver
Availability	Mouse Genotype	enlarged gallbladder	growth/size/body region phenotype	abnormal lean body mass	decreased body weight	increased body weight	postnatal growth retardation	enlarged liver
	Insr^tm1Jja/Insr^tm1Jja
	Insr^tm1Shs/Insr^tm1Shs
	Insr^tm1Khn/Insr^tm1Khn Tg(Ckmm-cre)5Khn/0 (conditional)		*
	Insr^tm1Khn/Insr^tm1Khn Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ (conditional)
	Insr^tm1Khn/Insr^tm1Khn Tg(Nes-cre)1Kln/0 (conditional)
	Insr^tm1Khn/Insr^tm1Khn Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Tg(Ins2-cre)25Mgn/0 (conditional)
	Insr^tm1Khn/Insr^tm1Khn Tg(Slc2a4-cre)546Dac/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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