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Symbol
Name
ID
Il2
interleukin 2
MGI:96548
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Decreased circulating IgA level
Decreased circulating IgG level
Decreased circulating IgG2 level
Defective B cell differentiation
Abnormality of metabolism/homeostasis
Decreased level of 1,5 anhydroglucitol in serum
Hyperbilirubinemia
Elevated circulating alpha-fetoprotein concentration
Elevated circulating C-reactive protein concentration
Elevated circulating hepatic transaminase concentration
Elevated circulating alkaline phosphatase concentration
Elevated erythrocyte sedimentation rate
Hyperglycemia
Glucose intolerance
Diabetes mellitus
Ketoacidosis
Joint swelling
Fever
Food intolerance
Hematuria
Pyuria
Decreased level of D-mannose in urine
Proteinuria
Increased circulating free T3
Increased circulating free T4 concentration
Decreased thyroid-stimulating hormone level
Disease(s) Associated with IL2
ataxia telangiectasia
atopic dermatitis
Behcet's disease
graft-versus-host disease
Graves' disease
pancreatic cancer
rheumatoid arthritis
systemic lupus erythematosus
type 1 diabetes mellitus

Mouse Phenotypes
decreased salivation
amyloidosis
increased circulating bilirubin level
abnormal circulating cytokine level
decreased circulating interferon-gamma level
decreased circulating interleukin-13 level
decreased circulating interleukin-17 level
increased circulating interleukin-17 level
decreased circulating interleukin-4 level
Availability Mouse Genotype
Il2tm1Hor/Il2tm1Hor
Il2tm1.1Kasm/Il2tm1.1Kasm
Ndor1Tg(UBC-cre/ERT2)1Ejb/?  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory