Symbol Name ID |
Il2
interleukin 2 MGI:96548 |
Darker colors indicate more annotations |
Human Phenotypes | Decreased circulating IgA level |
Decreased circulating IgG level |
Decreased circulating IgG2 level |
Defective B cell differentiation |
Abnormality of metabolism/homeostasis |
Decreased level of 1,5 anhydroglucitol in serum |
Hyperbilirubinemia |
Elevated circulating alpha-fetoprotein concentration |
Elevated circulating C-reactive protein concentration |
Elevated circulating hepatic transaminase concentration |
Elevated circulating alkaline phosphatase concentration |
Elevated erythrocyte sedimentation rate |
Hyperglycemia |
Glucose intolerance |
Diabetes mellitus |
Ketoacidosis |
Joint swelling |
Fever |
Food intolerance |
Hematuria |
Pyuria |
Decreased level of D-mannose in urine |
Proteinuria |
Increased circulating free T3 |
Increased circulating free T4 concentration |
Decreased thyroid-stimulating hormone level |
Disease(s) Associated with IL2 | ||||||||||||||||||||||||||
ataxia telangiectasia | ||||||||||||||||||||||||||
atopic dermatitis | ||||||||||||||||||||||||||
Behcet's disease | ||||||||||||||||||||||||||
graft-versus-host disease | ||||||||||||||||||||||||||
Graves' disease | ||||||||||||||||||||||||||
pancreatic cancer | ||||||||||||||||||||||||||
rheumatoid arthritis | ||||||||||||||||||||||||||
systemic lupus erythematosus | ||||||||||||||||||||||||||
type 1 diabetes mellitus |
Mouse Phenotypes | decreased salivation |
amyloidosis |
increased circulating bilirubin level |
abnormal circulating cytokine level |
decreased circulating interferon-gamma level |
decreased circulating interleukin-13 level |
decreased circulating interleukin-17 level |
increased circulating interleukin-17 level |
decreased circulating interleukin-4 level |
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Availability | Mouse Genotype | |||||||||
Il2tm1Hor/Il2tm1Hor | ||||||||||
Il2tm1.1Kasm/Il2tm1.1Kasm Ndor1Tg(UBC-cre/ERT2)1Ejb/? (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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