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Symbol
Name
ID 		Il10
interleukin 10
MGI:96537
Phenotype annotations related to skeleton
Darker colors indicate more annotations
Human Phenotypes
Joint hemorrhage
Trismus
Sinusitis
Interphalangeal joint erosions
Swan neck-like deformities of the fingers
Dupuytren contracture
Abnormality of the elbow
Limited elbow movement
Joint swelling
Limited shoulder movement
Joint stiffness
Stiff interphalangeal joints
Bone pain
Pathologic fracture
Vertebral compression fracture
Back pain
Osteopenia
Osteoporosis
Arthritis
Gout
Osteoarthritis
Rheumatoid arthritis
Polyarticular arthritis
Digital flexor tenosynovitis
Disease(s) Associated with IL10
Behcet's disease
coronary artery disease
factor VIII deficiency
graft-versus-host disease
granulomatosis with polyangiitis
multiple myeloma
pancreatic cancer
rheumatoid arthritis
Sjogren's syndrome
systemic lupus erythematosus
thrombocytopenia

Mouse Phenotypes
abnormal osteoblast differentiation
alveolar process atrophy
short femur
abnormal skeleton morphology
abnormal bone structure
decreased bone mineral content
decreased compact bone mass
abnormal trabecular bone morphology
decreased bone trabecula number
decreased trabecular bone mass
decreased trabecular bone thickness
abnormal skeleton physiology
abnormal bone mineralization
decreased bone strength
Availability Mouse Genotype
Il10tm1Cgn/Il10tm1Cgn
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory