Symbol Name ID |
Igf1
insulin-like growth factor 1 MGI:96432 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Decreased level of 1,5 anhydroglucitol in serum |
Elevated circulating hepatic transaminase concentration |
Hyperglycemia |
Diabetes mellitus |
Type II diabetes mellitus |
Insulin resistance |
Ketoacidosis |
Disease(s) Associated with IGF1 | |||||||
pancreatic cancer | |||||||
type 1 diabetes mellitus | |||||||
type 2 diabetes mellitus |
Mouse Phenotypes | homeostasis/metabolism phenotype |
decreased circulating glucose level |
increased circulating insulin level |
decreased circulating insulin-like growth factor I level |
increased circulating leptin level |
decreased circulating growth hormone level |
increased circulating growth hormone level |
abnormal glucose homeostasis |
increased urine potassium level |
increased urine sodium level |
insensitivity to growth hormone |
|
Availability | Mouse Genotype | |||||||||||
Igf1tm1.1Dlr/Igf1tm1.1Dlr | ||||||||||||
Igf1tm1.1Nros/Igf1tm1.1Nros | ||||||||||||
Igf1tm1Arge/Igf1tm1Arge | ||||||||||||
Igf1tm2.1Arge/Igf1tm2.1Arge | ||||||||||||
Igf1tm2Arge/Igf1tm2Arge | ||||||||||||
Igf1tm2Ts/Igf1tm2Ts | ||||||||||||
Igf1tm2Arge/Igf1tm2.1Arge | ||||||||||||
Igf1tm1Dlr/Igf1tm1Dlr Tg(Mx1-cre)1Cgn/0 (conditional) |
* | |||||||||||
Igf1tm1Dlr/Igf1tm1Dlr Tg(Alb1-cre)1Dlr/0 (conditional) |
||||||||||||
Igf1tm1Dlr/Igf1tm1Dlr Tg(Serpina1e-cre/ERT)1Sykr/0 (conditional) |
* | |||||||||||
Igf1tm2Arge/Igf1tm2Arge Tg(SERPINA1-cre)1Arge/0 (conditional) |
||||||||||||
Igf1tm2Arge/Igf1tm2.1Arge Tg(SERPINA1-cre)1Arge/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/23/2024 MGI 6.23 |
|
|