Symbol
Name
ID

Igf1
insulin-like growth factor 1
MGI:96432

Phenotype annotations related to growth/size/body

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Hepatosplenomegaly	Peritoneal abscess	Increased waist to hip ratio	Weight loss
Disease(s) Associated with IGF1	Hepatosplenomegaly	Peritoneal abscess	Increased waist to hip ratio	Weight loss
pancreatic cancer
type 2 diabetes mellitus

Mouse Phenotypes

growth/size/body region phenotype

decreased birth weight

decreased body weight

slow postnatal weight gain

abnormal postnatal growth/weight/body size

abnormal body size

decreased body length

decreased body size

disproportionate dwarf

proportional dwarf

postnatal growth retardation

abnormal embryonic growth/weight/body size

fetal growth retardation

Availability

Mouse Genotype

Igf1^tm1.1Dlr/Igf1^tm1.1Dlr

Igf1^tm1.1Nros/Igf1^tm1.1Nros

Igf1^tm1Arge/Igf1^tm1Arge

Igf1^tm1Ts/Igf1^tm1Ts

Igf1^tm2.1Arge/Igf1^tm2.1Arge

Igf1^tm2.1Nros/Igf1^tm2.1Nros

Igf1^tm2Arge/Igf1^tm2Arge

Igf1^tm2Ts/Igf1^tm2Ts

Igf1^tm1Ts/Igf1⁺

Igf1^tm2.1Nros/Igf1⁺

Igf1^tm2Arge/Igf1^tm2.1Arge

Igf1^tm1Dlr/Igf1^tm1Dlr
Tg(EIIa-cre)C5379Lmgd/0 (conditional)

Igf1^tm1Dlr/Igf1^tm1Dlr
Tg(Mx1-cre)1Cgn/0 (conditional)

Igf1^tm2Arge/Igf1^tm2Arge
Tg(SERPINA1-cre)1Arge/0 (conditional)

Igf1^tm2Arge/Igf1^tm2.1Arge
Tg(SERPINA1-cre)1Arge/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23