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Symbol
Name
ID
Iapp
islet amyloid polypeptide
MGI:96382
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Decreased level of 1,5 anhydroglucitol in serum
Hyperglycemia
Diabetes mellitus
Type II diabetes mellitus
Insulin resistance
Ketoacidosis
Disease(s) Associated with IAPP
type 1 diabetes mellitus
type 2 diabetes mellitus

Mouse Phenotypes
homeostasis/metabolism phenotype
decreased insulin secretion
abnormal homeostasis
hyperglycemia
increased circulating glucagon level
decreased circulating insulin level
increased circulating insulin level
impaired glucose tolerance
improved glucose tolerance
Availability Mouse Genotype
Iapptm1Sgm/Iapptm1Sgm *
Tg(Ins2-IAPP)L13Gjsc/0

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory