Symbol
Name
ID

Slc6a4
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
MGI:96285

Phenotype annotations related to behavior/neurological

Darker colors indicate more annotations

Human Phenotypes	Lack of spontaneous play	Impaired ability to form peer relationships	Autism	Addictive alcohol use	Hyperactivity	Attention deficit hyperactivity disorder	Inflexible adherence to routines	Motor stereotypy	Restrictive behavior
Disease(s) Associated with SLC6A4	Lack of spontaneous play	Impaired ability to form peer relationships	Autism	Addictive alcohol use	Hyperactivity	Attention deficit hyperactivity disorder	Inflexible adherence to routines	Motor stereotypy	Restrictive behavior
alcohol dependence
attention deficit hyperactivity disorder
autistic disorder

Mouse Phenotypes

enhanced behavioral response to xenobiotic

impaired behavioral response to xenobiotic

abnormal active avoidance behavior

enhanced conditioned place preference behavior

abnormal response to new environment

decreased exploration in new environment

behavioral despair

abnormal fear/anxiety-related behavior

abnormal anxiety-related response

abnormal response to novel object

abnormal response to social novelty

increased startle reflex

decreased locomotor activity

hyperactivity

increased stereotypic behavior

abnormal sleep pattern

abnormal thermal nociception

abnormal social investigation

social withdrawal

decreased vocalization

Availability

Mouse Genotype

Slc6a4^{Gt1(IRESBetageo)lLex}/Slc6a4^{Gt1(IRESBetageo)lLex}

Slc6a4^tm1.1Rbl/Slc6a4^tm1.1Rbl

Slc6a4^tm1Grch/Slc6a4^tm1Grch

Slc6a4^tm1Kpl/Slc6a4^tm1Kpl

Slc6a4^tm2.1Rbl/Slc6a4^tm2.1Rbl

Slc6a4^tm1Kpl/Slc6a4⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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